HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.
Recombinant HuD is a useful reagent to charcterize and discover new mRNA regulatory elements.
Recombinant HuD Protein
The study of RNA regulatory elements
Storage instructions Heat stable , shipped at ambient temp. Upon delivery aliquot and store in fridge , longterm storage at -20°C. Storage buffer PBS, pH 7.2 Purification notes
Expressed in E.Coli and purified by affinity chromatography
Gel retardation analysis of HuD interaction with fos AUUA site
10ug HuD protein
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