CLONEGENE

CLONEGENE

TAG Antibodies

Myc tag Antibody 9E10

Myc tag 5A5 (CHIP grade)

Anti-GST Monoclonal

Anti-GFP [F56-6A1.2.3]

Anti-GFP tag Monoclonal

Anti-6His tag Monoclonal

Anti- DDDDK

Neuronal Markers

Anti-Hud Antibody 16C12

Anti-HuD Mab 15A9

Anti-HuD/HuC/HuB 16A11

Anti-HuD/HuC/HuB Mab 8B3

Paraneoplastic Antigens

Hu antigen

Anti-Neoantigen

Anti-HuDE

Tumor Checkpoint Pathway

anti-CD11b

Anti CD119

Anti-CD20 Mab 2H7

Anti-CD19 Mab 4G7

Anti CD152/h CTLA4

Anti-PD1 Monoclonal J110

Anti-PD-L1 Monoclonal

Anti TIGIT

Anti-EGFR mab 225

Gene Regulation

Anti-Dicer MAb 4A6

Anti-Dicer Mab 13D6

Anti-Dicer 13D6R

HuR Antibody mab 19F12

HuR antibody 4C8

HuD RNA binding Protein

Viral Antibodies

Anti-HIV GP120 Mab 5B12

Anti-Flu A Mab HB65

Anti-Zika Virus

Anti-West Nile virus

Anti-Dengue Virus

Anti-JEV Virus

Anti-SARS-COV-2 Spike

Anti-SARS-COV-2 NP

ORDER INFO

Distributors

CG0098 - ChIP grade Anti-HuR mouse monoclonal antibody 4C8

ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene.[1][2]

The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.[3]

A populat technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby  analyse gene expression in a particualr tissue. Monoclonal  4C8 was selected by its ability  to  bind to the HuR/mRNA complex  and thus is  very usefull for  EMSA, ChIP and CLIP studies 




Product name  
Anti HuR  

Description   
Mouse monoclonal to HuR  protein  capable of  supershifting HuR/RMNA complex on EMSA  and ideal for ChIP 
 
Tested applications 
 ELISA, WB ,  IHC, IHC-FFPE, ChIP, CLIP, EMSA supershift 

Immunogen
Unique HuR peptide

Form 
Liquid

Storage instructions
 Heat stable , shipped at ambient  temp  Upon delivery aliquot and store in fridge , longterm storage at  -20°C.

Storage buffer
PBS, pH 7.2

Concentration
 100 µl at 1.0  mg/ml

Purification notes
Purified

Clonality
Monoclonal  4C8

Isotype
IgG1
 


Suoer shift of HuR /RNA complex via 4C8
 
 


REFERENCES

miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth. Nature Communications. 2015;6:8725. doi:10.1038/ncomms9725.

Neuroprotection requires the functions of the RNA-binding protein HuR Cell Death & Differentiation 22, 703-718





Standard Unit 
100ug of 4C8

100ug 4C8

$360.00



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Alternatively you can email your purchase requisition with P.O. number, catalog numbers, quantity, and shipping & billing addresses to:

ORDER@CLONEGENE.COM 

 Inquire for  bulk quotes ( up to 20mg)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" 


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