ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1gene.[1][2]
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.[3]
A populat technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particualr tissue. Monoclonal 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very usefull for EMSA, ChIP and CLIP studies
Product name
Anti HuR
Description
Mouse monoclonal to HuR protein capable of supershifting HuR/RMNA complex on EMSA and ideal for ChIP Tested applications ELISA, WB , IHC, IHC-FFPE, ChIP, CLIP, EMSA supershift
Immunogen
Unique HuR peptide
Form Liquid
Storage instructions Heat stable , shipped at ambient temp Upon delivery aliquot and store in fridge , longterm storage at -20°C.
