CLONEGENE

HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene.^[4][5]The HuD/ELAVL4 protein is an RNA-binding protein.^[6]HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.^[7][8]

 

The 16C12  monoclonal antibody is the reagent of choice to determine the expression of HuD (ELAVL4) by IHC or western blotting.  It is known to react with human, mouse, rat, and zebrafish HuD.  It was generated against a unique peptide found in HuD and does not bind to HuC, HeLN-1 or HuR. 
The figure below shows the utility of 16C12. Click on the image to view the published paper.

 
Tested applications
ELISA, WB ,  IHC

Immunogen 

Synthetic peptide

Form
Liquid

Storage instructions
Heat stable , shipped at ambient  temp  Upon delivery aliquot and store in fridge , longterm storage at  -20°C.

Storage buffer
PBS, pH 7.2

Concentration
 100 µl at 1.0  mg/ml 

Clonality

Monoclonal 16C12

Isotype
IgG2b