HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.[4][5]
The 16A11 anti-Hu monoclonal is now a classic reagent for the identification of neurons.
Product name
MAb 16A11
Description
Monoclonal antibody against HuD and HuC proteins
Tested applications
ELISA, WB , IHC, IF , IHC -FFPE
Immunogen
Peptide
Form Liquid
Storage instructions Heat stable , shipped at ambient temp Upon delivery aliquot and store in fridge , longterm storage at -20°C.
Storage buffer PBS, pH 7.2
Concentration 100 µl at 1.0 mg/ml
Purification notes
purified
Clonality
Monoclonal 16A11
Isotype
IgG2b
identification of neurons via 16A11
Standard Package
100ug
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