| Anti-HuR, Anti-ELAVL1, Anti-HuA ( Monoclonal 19F12 ) cat# CG001 |
HuR (also called Elavl-1 or HuA) is a protein that
binds to specific AU-rich elements in a mRNA and thereby upregulates its
expression. The protein contains three RRM type RNA binding domains.
The first and second RNA binding domains interact with the Au-rich
element. Although it is essential for activity, the function of the
third RNA binding domain remains unknown. HuR and is a member of a
family of proteins called the elav-like proteins. The other members,
HuD, HuC, and HEL-N1 are predominantly expressed in neurons. Mab
CG001 (monoclonal 19F12) was generated against a unique HuR peptide and
does not react with HuD, HuC, or Hel-N1. It is ideal for western blot
and immunohistochemistry applications and has been featured in many
scientific publications. The picture below shows an ovarian tumor
stained with 19F12.
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Raised in Mouse
Clonality Monoclonal Clone number 19F12
Isotype IgG1
Purification notes Precipitated from tissue culture supernatant.
Storage buffer High stability buffer , shipped at ambient temperature , store at -20
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