| Anti-Hu Antibody - Monoclonal Antibody 16A11 - Catalogue Number CG005 |
Mouse monoclonal 16A11 is excellent for the
detection of Elav proteins HuD, Hel-N1 and HuC by western blot and
immunohistochemistry. The expression of Elav proteins is a biomarker for neuronal cells, small cell lung cancers and melanomas. 16A11 has been extensively cited in many publications that study neuronal differentiation. 16A11 is known to react with human , mouse, rat, and
zebrafish Hud, HuC and Hel-N1 proteins. Monoclonal antibody 16A11 is an IgG2b and was generated
against a peptide found in HuD, HuC and Hel-N1 but not in HuR.
Antigen Peptide from Human Hu (Elav)
Reactivity Human, mouse, rat and
zebrafish
Applications WB, IHC, IHC (P), ELISA
Form Purified
Reference Szabo A, Dalmau J,
Manley G, et al. (1991).HuD, a paraneoplastic encephalomyelitis antigen,
contains RNA-binding domains and is homologous to Elav and Sex-lethal. Cell
67 (2): 325
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The picture above shows neurons (green) identified by staining with mab 16A11. Click on the picture to go to the original paper on the use of 16A11 in the efficient generation of retinal progenitor cells from human embryonic stem cells
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