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Myc tag Antibody 9E10

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Anti-Hud Antibody 16C12

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Anti-CD20 Mab 2H7

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Anti-PD1 Monoclonal J110

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Anti TIGIT

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Gene Regulation

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Anti-Dicer 13D6R

HuR Antibody mab 19F12

HuR antibody 4C8

HuD RNA binding Protein

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ORDER INFO

Distributors

CG 0137 Mouse Monoclonal 13E7 to TIGIT, VSTM3, WUCAM (T cell immunoreceptor with Ig and ITIM domains)

TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is one newly discovered immune receptor on some percentage of T cells and Natural Killer Cells(NK).[1] It is also identified as WUCAM[2] and Vstm3.[3] TIGIT could bind to CD155(PVR) on dendritic cells(DCs), macrophages, etc. with high affinity, and also to CD112(PVRL2) with lower affinity.[1]

Research has shown that TIGIT-Fc fusion protein could interact with PVR on dendritic cells and increase its IL-10 secretion level/decrease its IL-12 secretion level under LPS stimulation, and also inhibit T cell activation in vivo.[1] TIGIT's inhibition of NK cytotoxicity can be blocked by antibodies against its interaction with PVR and the activity is directed through its ITIM domain[4]


Product name  
Anti-TIGIT 


Description 
 Mouse Monoclonal to TIGIT  
 

Tested applications
ELISA, WB ,  IHC

Immunogen 
TIGIT


Form
Liquid

Storage instructions
 Heat stable , shipped at ambient  temp  Upon delivery aliquot and store in fridge , longterm storage at  -20°C.

Storage buffer
PBS, pH 7.2

Concentration
 100 µl at 1.0  mg/ml

Purification notes
Purified from hybridoma supernatant 

Clonality
Monoclonal  13E7


Isotype
IgG1

 
IHC on mouse spleen


Standard Size
100ug 

100ug anti-TIGIT 13E7

$370.00



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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" 


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