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Myc tag Antibody 9E10

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Anti-Hud Antibody 16C12

Anti-HuD Mab 15A9

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HuR Antibody mab 19F12

HuR antibody 4C8

HuD RNA binding Protein

Viral Antibodies

Anti-HIV GP120 Mab 5B12

Anti-Flu A Mab HB65

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Anti-West Nile virus

Anti-Dengue Virus

Anti-JEV Virus

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ORDER INFO

Distributors

CG00863 Anti-Dengue Virus Antibody


Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus.[1][2] Five serotypes of the virus have been found,[3][4] all of which can cause the full spectrum of disease.[1] Nevertheless, scientists are finding their understanding of dengue virus may be simplistic, as rather than distinct antigenic groups there appears to be a continuum.[5] This same study identified 47 strains of dengue virus.[6] Additionally, coinfection with and lack of rapid tests for zika virus and chikungunya complicate matters in real world infections.

The DENV E (envelope) protein, found as a dimer on the surface of the mature viral particle, is important in the initial attachment of this particle to the host cell. Each E protein monomer comprises three ectodomains, ED1 to ED3, and a trans-membrane segment. ED2 includes the dimerization interface, two glycosylation sites, and the peptide of fusion with the cellular membrane. ED3 is a continuous polypeptide segment; its fold is compact and immunoglobulin-like.[24][25] Dengue virus is transmitted by a mosquito known as Aedes. Several molecules which interact with the viral E protein (ICAM3-grabbing non-integrin,[26] CD209,[27] Rab 5,[28] GRP 78,[29] and the mannose receptor [30]) have been shown to be important factors mediating attachment and viral entry.[25] The membrane form of Ribosomal protein SA may also be involved in the attachment.[31] Recombinant domains of the E protein are used as well-defined antigens in the serological detection of antibodies directed against dengue virus and as immunogens in vaccine candidates.[32][33][34]

CG00863 is a high affinity  rabbit IgG directed against the E protein of Dengue virus.



Name
Anti-Dengue Virus E  protein
    
Reactivity 
DENV-1, DENV-2, DENV-3 and DENV-4 serotypes.
  
Tested applications
IHC, WB, neutralization, ELISA.

Immunogen 
E protein

Form
Liquid

Storage instructions
Heat stable , shipped at ambient  temp  Upon delivery aliquot and store in fridge , long term storage at  -20°C.

Storage buffer
PBS, pH 7.2

Purification notes
Purified via protein A 

Isotype 
Rabbit  IgG
 


 
 
 


100ug  of  Anti-Dengue Virus Antibody  

CG00863 100ug

$390.00

To order, please  use our online cart  buttons on each page. You can use  Paypal  or Major Credit cards.

Alternatively you can email your purchase requisition with P.O. number, catalog numbers, quantity, and shipping & billing addresses to:

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" 


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