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ORDER INFO

Distributors

CG0545 Anti-Japanese Encephalitis Virus Antibody


JEV is a virus from the family Flaviviridae, part of the Japanese encephalitis serocomplex of 9 genetically and antigenically related viruses, some which are particularly severe in horses, and four known to infect humans including West Nile virus.[9] The enveloped virus is closely related to the West Nile virus and the St. Louis encephalitis virus. The positive sense single-stranded RNA genome is packaged in the capsid which is formed by the capsid protein. The outer envelope is formed by envelope protein and is the protective antigen. It aids in entry of the virus into the inside of the cell. The genome also encodes several nonstructural proteins (NS1, NS2a, NS2b, NS3, N4a, NS4b, NS5). NS1 is produced as secretory form also. NS3 is a putative helicase, and NS5 is the viral polymerase. It has been noted that Japanese encephalitis infects the lumen of the endoplasmic reticulum (ER)[10][11] and rapidly accumulates substantial amounts of viral proteins. Based on the envelope gene, there are five genotypes (I–V). The Muar strain, isolated from a patient in Malaya in 1952, is the prototype strain of genotype V. Genotype IV appears to be the ancestral strain, and the virus appears to have evolved in the Indonesian–Malaysian region. The first clinical reports date from 1870, but the virus appears to have evolved in the mid-16th century. Over sixty complete genomes of this virus had been sequenced by 2010.

CG0545 is a high affinity rabbit antibody selectively directed against JE virus




Name
Anti-JEV
    
Reactivity 
Humam, mouse, rat.
  
Tested applications
IHC, WB, Flow, neutralization. 

Immunogen 
JEV

Form
Liquid

Storage instructions
Heat stable , shipped at ambient  temp  Upon delivery aliquot and store in fridge , long term storage at  -20°C.

Storage buffer
PBS, pH 7.2

Purification notes
Purified via protein A 

Isotype 
Rabbit  IgG
 


 
 
 


100ug  of  Anti-JEV

100ug Rabbit anti-JEV

$390.00



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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" 


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